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1

The future of metabolic engineering and synthetic biology: Towards a systematic practice

Vikramaditya G. Yadav, Marjan De Mey, Chin Giaw Lim, Parayil Kumaran Ajikumar, Gregory Stephanopoulos

Journal:

Metabolic Engineering

Année:

2012

Langue:

english

Fichier:

PDF, 1.05 MB

english, 2012

2

Citrobacter werkmanii, a new candidate for the production of 1,3-propanediol: strain selection and carbon source optimization

Maervoet, Veerle E. T., Beauprez, Joeri, De Maeseneire, Sofie L., Soetaert, Wim K., De Mey, Marjan

Journal:

Green Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 1023 KB

english, 2012

3

Minimizing acetate formation inE. colifermentations

Marjan De Mey, Sofie De Maeseneire, Wim Soetaert, Erick Vandamme

Journal:

Journal of Industrial Microbiology & Biotechnology

Année:

2007

Langue:

english

Fichier:

PDF, 391 KB

english, 2007

4

Development of an in vivo glucosylation platform by coupling production to growth: Production of phenolic glucosides by a glycosyltransferase of Vitis vinifera

De Bruyn, Frederik, De Paepe, Brecht, Maertens, Jo, Beauprez, Joeri, De Cocker, Pieter, Mincke, Stein, Stevens, Christian, De Mey, Marjan

Journal:

Biotechnology and Bioengineering

Année:

2015

Langue:

english

Fichier:

PDF, 945 KB

english, 2015

5

Tailor-made transcriptional biosensors for optimizing microbial cell factories

De Paepe, Brecht, Peters, Gert, Coussement, Pieter, Maertens, Jo, De Mey, Marjan

Journal:

Journal of Industrial Microbiology & Biotechnology

Année:

2017

Langue:

english

Fichier:

PDF, 914 KB

english, 2017

6

Comparison of DNA and RNA quantification methods suitable for parameter estimation in metabolic modeling of microorganisms

Marjan De Mey, Gaspard Lequeux, Jo Maertens, Sofie De Maeseneire, Wim Soetaert, Erick Vandamme

Journal:

Analytical Biochemistry

Année:

2006

Langue:

english

Fichier:

PDF, 204 KB

english, 2006

7

Development and application of a differential method for reliable metabolome analysis in Escherichia coli

Hilal Taymaz-Nikerel, Marjan de Mey, Cor Ras, Angela ten Pierick, Reza M. Seifar, Jan C. van Dam, Joseph J. Heijnen, Walter M. van Gulik

Journal:

Analytical Biochemistry

Année:

2009

Langue:

english

Fichier:

PDF, 335 KB

english, 2009

8

Microbial succinic acid production: Natural versus metabolic engineered producers

Joeri J. Beauprez, Marjan De Mey, Wim K. Soetaert

Journal:

Process Biochemistry

Année:

2010

Langue:

english

Fichier:

PDF, 665 KB

english, 2010

9

Catching prompt metabolite dynamics in Escherichia coli with the BioScope at oxygen rich conditions

Marjan De Mey, Hilal Taymaz-Nikerel, Gino Baart, Hendrik Waegeman, Jo Maertens, Joseph J. Heijnen, Walter M. van Gulik

Journal:

Metabolic Engineering

Année:

2010

Langue:

english

Fichier:

PDF, 1.32 MB

english, 2010

10

Effect oficlRandarcAknockouts on biomass formation and metabolic fluxes inEscherichiacoliK12 and its implications on understanding the metabolism ofEscherichia coliBL21 (DE3)

Hendrik Waegeman, Joeri Beauprez, Helena Moens, Jo Maertens, Marjan De Mey, Maria R Foulquié-Moreno, Joseph J Heijnen, Daniel Charlier, Wim Soetaert

Journal:

BMC Microbiology

Année:

2011

Langue:

english

Fichier:

PDF, 993 KB

english, 2011

11

Promoter knock-in: a novel rational method for the fine tuning of genes

Marjan De Mey, Jo Maertens, Sarah Boogmans, Wim K Soetaert, Erick J Vandamme, Raymond Cunin, Maria R Foulquié-Moreno

Journal:

BMC Biotechnology

Année:

2010

Langue:

english

Fichier:

PDF, 692 KB

english, 2010

12

Construction and model-based analysis of a promoter library forE. coli: an indispensable tool for metabolic engineering

Marjan De Mey, Jo Maertens, Gaspard J Lequeux, Wim K Soetaert, Erick J Vandamme

Journal:

BMC Biotechnology

Année:

2007

Langue:

english

Fichier:

PDF, 2.80 MB

english, 2007

13

Development of a selection system for the detection of L-ribose isomerase expressing mutants ofEscherichia coli

Cassandra De Muynck, Jef Van der Borght, Marjan De Mey, Sofie L. De Maeseneire, Inge N. A. Van Bogaert, Joeri Beauprez, Wim Soetaert, Erick Vandamme

Journal:

Applied Microbiology and Biotechnology

Année:

2007

Langue:

english

Fichier:

PDF, 249 KB

english, 2007

14

Transient metabolic modeling ofEscherichia coliMG1655 and MG1655 ΔackA-pta, ΔpoxBΔpppc ppc-p37 for recombinant β-galactosidase production

Marjan De Mey, Gaspard J. Lequeux, Joeri J. Beauprez, Jo Maertens, Hendrik J. Waegeman, Inge N. Van Bogaert, Maria R. Foulquié-Moreno, Daniel Charlier, Wim K. Soetaert, Peter A. Vanrolleghem, Erick J.

Journal:

Journal of Industrial Microbiology & Biotechnology

Année:

2010

Langue:

english

Fichier:

PDF, 480 KB

english, 2010

15

Microbial metabolomics: past, present and future methodologies

Mlawule R. Mashego, Karl Rumbold, Marjan De Mey, Erick Vandamme, Wim Soetaert, Joseph J. Heijnen

Journal:

Biotechnology Letters

Année:

2007

Langue:

english

Fichier:

PDF, 361 KB

english, 2007

16

Effect oficlRandarcAdeletions on physiology and metabolic fluxes inEscherichia coliBL21 (DE3)

Hendrik Waegeman, Jo Maertens, Joeri Beauprez, Marjan De Mey, Wim Soetaert

Journal:

Biotechnology Letters

Année:

2012

Langue:

english

Fichier:

PDF, 556 KB

english, 2012

17

Importance of the cytochrome P450 monooxygenase CYP52 family for the sophorolipid-producing yeast Candida bombicola

Inge N.A. Van Bogaert, Marjan De Mey, Dirk Develter, Wim Soetaert, Erick J. Vandamme

Journal:

FEMS Yeast Research

Année:

2010

Fichier:

PDF, 34 KB

2010

18

Cloning, sequence analysis and heterologous expression of the Myrothecium gramineum orotidine-5′-monophosphate decarboxylase gene

Sofie L. De Maeseneire, Manu R.M. De Groeve, Thierry Dauvrin, Marjan De Mey, Wim Soetaert, Erick J.M.C. Vandamme

Journal:

FEMS Microbiology Letters

Année:

2006

Langue:

english

Fichier:

PDF, 763 KB

english, 2006

19

Comparison of Different Strategies to Reduce Acetate Formation in Escherichia coli

Marjan de Mey, Gaspard J. Lequeux, Joeri J. Beauprez, Jo Maertens, Ellen Van Horen, Wim K. Soetaert, Peter A. Vanrolleghem, Erick J. Vandamme

Journal:

Biotechnology Progress

Année:

2007

Langue:

english

Fichier:

PDF, 380 KB

english, 2007

20

A constitutive expression system for high-throughput screening

Dirk Aerts, Tom Verhaeghe, Marjan De Mey, Tom Desmet, Wim Soetaert

Journal:

Engineering in Life Sciences

Année:

2011

Langue:

english

Fichier:

PDF, 405 KB

english, 2011

21

Comparison of protein quantification and extraction methods suitable for E. coli cultures

Marjan De Mey, Gaspard J. Lequeux, Jo Maertens, Cassandra I. De Muynck, Wim K. Soetaert, Erick J. Vandamme

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 189 KB

english, 2008

22

Validation study of 24 deepwell microtiterplates to screen libraries of strains in metabolic engineering

Hendrik Waegeman, Joeri Beauprez, Jo Maertens, Marjan De Mey, Lieven Demolder, Maria R. Foulquié-Moreno, Nico Boon, Daniel Charlier, Wim Soetaert

Journal:

Journal of Bioscience and Bioengineering

Année:

2010

Langue:

english

Fichier:

PDF, 561 KB

english, 2010

23

Enhancing the Microbial Conversion of Glycerol to 1,3-Propanediol Using Metabolic Engineering

Maervoet, Veerle E. T., De Mey, Marjan, Beauprez, Joeri, De Maeseneire, Sofie, Soetaert, Wim K.

Journal:

Organic Process Research & Development

Année:

2011

Langue:

english

Fichier:

PDF, 1.73 MB

english, 2011

24

Changes in substrate availability in Escherichia coli lead to rapid metabolite, flux and growth rate responses

Taymaz-Nikerel, Hilal, De Mey, Marjan, Baart, Gino, Maertens, Jo, Heijnen, Joseph J., van Gulik, Walter

Journal:

Metabolic Engineering

Année:

2013

Langue:

english

Fichier:

PDF, 2.17 MB

english, 2013

25

Integrating the Protein and Metabolic Engineering Toolkits for Next-Generation Chemical Biosynthesis

Pirie, Christopher M., De Mey, Marjan, Prather, Kristala L. Jones, Ajikumar, Parayil Kumaran

Journal:

ACS Chemical Biology

Année:

2013

Langue:

english

Fichier:

PDF, 1.57 MB

english, 2013

26

Biotechnological production of natural zero-calorie sweeteners

Philippe, Ryan N, De Mey, Marjan, Anderson, Jeff, Ajikumar, Parayil Kumaran

Journal:

Current Opinion in Biotechnology

Année:

2014

Langue:

english

Fichier:

PDF, 1010 KB

english, 2014

27

One step DNA assembly for combinatorial metabolic engineering

Coussement, Pieter, Maertens, Jo, Beauprez, Joeri, Van Bellegem, Wouter, De Mey, Marjan

Journal:

Metabolic Engineering

Année:

2014

Langue:

english

Fichier:

PDF, 1.59 MB

english, 2014

28

Increasing recombinant protein production in Escherichia coli K12 through metabolic engineering

Waegeman, Hendrik, De Lausnay, Stijn, Beauprez, Joeri, Maertens, Jo, De Mey, Marjan, Soetaert, Wim

Journal:

New Biotechnology

Année:

2013

Langue:

english

Fichier:

PDF, 742 KB

english, 2013

29

1,3-propanediol production withCitrobacter werkmaniiDSM17579: effect of adhaDknock-out

Maervoet, Veerle ET, De Maeseneire, Sofie L, Avci, Fatma G, Beauprez, Joeri, Soetaert, Wim K, De Mey, Marjan

Journal:

Microbial Cell Factories

Année:

2014

Langue:

english

Fichier:

PDF, 467 KB

english, 2014

30

Multivariate modular metabolic engineering for pathway and strain optimization

Biggs, Bradley Walters, De Paepe, Brecht, Santos, Christine Nicole S, De Mey, Marjan, Kumaran Ajikumar, Parayil

Journal:

Current Opinion in Biotechnology

Année:

2014

Langue:

english

Fichier:

PDF, 779 KB

english, 2014

31

Laparoscopic Management of Insulinoma in a Child with Multiple Endocrine Neoplasia Type 1

Vogelaere, Kristel De, Schepper, Jean De, Vanhoeij, Marjan, Mey, Johan De, Goossens, Anita, Vanbesien, Jesse, Backer, Antoine De, Delvaux, Georges

Journal:

Journal of Laparoendoscopic & Advanced Surgical Techniques

Année:

2006

Langue:

english

Fichier:

PDF, 1.43 MB

english, 2006

32

Biotechnological advances in UDP-sugar based glycosylation of small molecules

De Bruyn, Frederik, Maertens, Jo, Beauprez, Joeri, Soetaert, Wim, De Mey, Marjan

Journal:

Biotechnology Advances

Année:

2015

Langue:

english

Fichier:

PDF, 1.33 MB

english, 2015

33

Towards a carbon-negative sustainable bio-based economy

Vanholme, Bartel, Desmet, Tom, Ronsse, Frederik, Rabaey, Korneel, Breusegem, Frank Van, Mey, Marjan De, Soetaert, Wim, Boerjan, Wout

Journal:

Frontiers in Plant Science

Année:

2013

Langue:

english

Fichier:

PDF, 560 KB

english, 2013

34

Comparative fluxome and metabolome analysis for overproduction of succinate in Escherichia coli

Taymaz-Nikerel, Hilal, De Mey, Marjan, Baart, Gino J. E., Maertens, Jo, Foulquié-Moreno, Maria Remedios, Charlier, Daniel, Heijnen, Joseph J., van Gulik, Walter M.

Journal:

Biotechnology and Bioengineering

Année:

2015

Langue:

english

Fichier:

PDF, 895 KB

english, 2015

35

Putting RNA to work: Translating RNA fundamentals into biotechnological engineering practice

Peters, Gert, Coussement, Pieter, Maertens, Jo, Lammertyn, Jeroen, De Mey, Marjan

Journal:

Biotechnology Advances

Année:

2015

Langue:

english

Fichier:

PDF, 832 KB

english, 2015

36

Metabolic engineering of Escherichia coli into a versatile glycosylation platform: production of bio-active quercetin glycosides

De Bruyn, Frederik, Van Brempt, Maarten, Maertens, Jo, Van Bellegem, Wouter, Duchi, Dries, De Mey, Marjan

Journal:

Microbial Cell Factories

Année:

2015

Langue:

english

Fichier:

PDF, 1.36 MB

english, 2015

37

Efficient utilization of pentoses for bioproduction of the renewable two-carbon compounds ethylene glycol and glycolate

Pereira, Brian, Li, Zheng-Jun, De Mey, Marjan, Giaw Lim, Chin, Zhang, Haoran, Hoeltgen, Claude, Stephanopoulos, Gregory

Journal:

Metabolic Engineering

Année:

2015

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2015

38

Orthogonal assays clarify the oxidative biochemistry of Taxol P450 CYP725A4

Biggs, Bradley Walters, Rouck, John Edward, Kambalyal, Amogh, Arnold, William, Lim, Chin-Giaw, de Mey, Marjan, O'Neil-Johnson, Mark, Starks, Courtney M., Das, Aditi, Ajikumar, Parayil Kumaran

Journal:

ACS Chemical Biology

Année:

2016

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2016

39

Overcoming heterologous protein interdependency to optimize P450-mediated Taxol precursor synthesis in Escherichia coli

Biggs, Bradley Walters, Lim, Chin Giaw, Sagliani, Kristen, Shankar, Smriti, Stephanopoulos, Gregory, De Mey, Marjan, Ajikumar, Parayil Kumaran

Journal:

Proceedings of the National Academy of Sciences

Année:

2016

Langue:

english

Fichier:

PDF, 1.02 MB

english, 2016

40

Engineering a novel biosynthetic pathway in Escherichia coli for production of renewable ethylene glycol

Pereira, Brian, Zhang, Haoran, De Mey, Marjan, Lim, Chin Giaw, Li, Zheng-Jun, Stephanopoulos, Gregory

Journal:

Biotechnology and Bioengineering

Année:

2016

Langue:

english

Fichier:

PDF, 523 KB

english, 2016

41

High yield 1,3-propanediol production by rational engineering of the 3-hydroxypropionaldehyde bottleneck in Citrobacter werkmanii

Maervoet, Veerle E. T., De Maeseneire, Sofie L., Avci, Fatma G., Beauprez, Joeri, Soetaert, Wim K., De Mey, Marjan

Journal:

Microbial Cell Factories

Année:

2016

Langue:

english

Fichier:

PDF, 1.67 MB

english, 2016

42

Not just PCR: using modified oligonucleotides for recursive cloning

Van Hove, Bob, Guidi, Chiara, De Wannemaeker, Lien, Maertens, Jo, De Mey, Marjan

Journal:

New Biotechnology

Année:

2016

Langue:

english

Fichier:

PDF, 60 KB

english, 2016

43

Automated de novo design of ligand responsive RNA devices

Peters, Gert, Maertens, Jo, Lammertyn, Jeroen, De Mey, Marjan

Journal:

New Biotechnology

Année:

2016

Langue:

english

Fichier:

PDF, 46 KB

english, 2016

44

Direct combinatorial pathway optimization

Coussement, Pieter, Bauwens, David, Maertens, Jo, de Mey, Marjan

Journal:

ACS Synthetic Biology

Année:

2016

Langue:

english

Fichier:

PDF, 2.44 MB

english, 2016

45

Heterologous expression and characterization of plant Taxadiene-5α-Hydroxylase (CYP725A4) in Escherichia coli

Rouck, John Edward, Biggs, Bradley Walters, Kambalyal, Amogh, Arnold, William R., De Mey, Marjan, Ajikumar, Parayil Kumaran, Das, Aditi

Journal:

Protein Expression and Purification

Année:

2017

Langue:

english

Fichier:

PDF, 3.00 MB

english, 2017

46

Recursive DNA Assembly Using Protected Oligonucleotide Duplex Assisted Cloning (PODAC)

Van Hove, Bob, Guidi, Chiara, De Wannemaeker, Lien, Maertens, Jo, De Mey, Marjan

Journal:

ACS Synthetic Biology

Année:

2017

Langue:

english

Fichier:

PDF, 623 KB

english, 2017

47

Standardization in synthetic biology: an engineering discipline coming of age

Decoene, Thomas, De Paepe, Brecht, Maertens, Jo, Coussement, Pieter, Peters, Gert, De Maeseneire, Sofie L., De Mey, Marjan

Journal:

Critical Reviews in Biotechnology

Année:

2017

Langue:

english

Fichier:

PDF, 1.34 MB

english, 2017

48

Challenges in the microbial production of flavonoids

Delmulle, Tom, De Maeseneire, Sofie L., De Mey, Marjan

Journal:

Phytochemistry Reviews

Année:

2017

Langue:

english

Fichier:

PDF, 1.09 MB

english, 2017

49

A sigma factor toolbox for orthogonal gene expression in Escherichia coli

Bervoets, Indra, Van Brempt, Maarten, Van Nerom, Katleen, Van Hove, Bob, Maertens, Jo, De Mey, Marjan, Charlier, Daniel

Journal:

Nucleic Acids Research

Année:

2018

Langue:

english

Fichier:

PDF, 3.70 MB

english, 2018

50

Toward predictable 5'UTRs in Saccharomyces cerevisiae: Development of a yUTR calculator

Decoene, Thomas, Peters, Gert, De Maeseneire, Sofie, De Mey, Marjan

Journal:

ACS Synthetic Biology

Année:

2018

Langue:

english

Fichier:

PDF, 1.49 MB

english, 2018